Top 10 Biggest Biotechnology Companies in the World

Biotechnology is a combination of biology and technology and is the cause of developing medical drugs, medical devices, diagnostic products, biofuels, and pollution control technologies. The industry companies are mainly engaged in offering novel solutions to diseases. It should be remembered that drug development firms go through lengthy trials and approvals before they can decide on any new drug entity as being commercially viable.

Among the biotech era’s big pharma, companies invest in research and development. Drug candidates in such companies then fall under strict scrutiny by regulators before they receive commercialization. Investors, in the majority of instances, are forced to wait for a very long time for years for their fantasies to come true whether these drugs will eventually be successful or profitable.

In spite of all these rigs, there have emerged some biotechnology companies which are now publicly traded industry leaders. The top 10, listed by trailing 12-month revenue, are U.S.-and Canadian-based publicly traded companies, directly or indirectly through American depository receipts (ADRs). Some of the foreign rivals report revenues every other quarter, so the potential lag in reporting revenues.

All net income and revenue figures are reported for Q3 2024 as of November 17, 2024, market cap data. One-year trailing total returns as of November 15, 2024, are sourced from Morningstar, while financial information is provided by TradingView. Such industry giants continue to dominate, innovating in spite of many problems that are raised by the drug approval process and competing markets.

Top 10 World’s Best Performing Biomedical Companies

1- Novo Nordisk A/S

Novo Nordisk A/S is a Danish health and pharmaceutical company based in Bagsværd with factories in and around eight nations and five of them have branches. It is quite difficult attempting and trying to combat diabetes, obesity, and rare bleeding diseases, and proprietary drugs and products are used for the treatment of haemophilia patients in replacement hormone therapy and growth hormone therapy.

Some of the key brands over which Novo sells its medicines include Levemir, NovoLog, NovoEight, and Novolin R. Novo Nordisk in November 2021 also entered an agreement to acquire Dicerna Pharmaceuticals and its research technology platform involving RNAi insights to extend therapeutic areas on the company’s purview.

2- Johnson & Johnson

Johnson & Johnson is a multinational American health care corporation. The company makes health care medical devices and medicine, as well as consumer packaged products. Its wide range of flagship brands across the principal line of pharmaceuticals; infant and pediatric; and first-aid products have earned universal acceptance under dominant brand names: Band-Aid, Neutrogena Skin and Beauty, Clean & Clear, and Acuvue. In November 2021, the remainder company, a biotechnology and medical technology company, announced that it would separate the consumer health business into an independent publicly traded company.

Johnson & Johnson’s New Brunswick corporate headquarters is an American-valued multinational corporation, thereby qualifying to be involved in the production of medical devices, pharmaceutical medicine, and consumer packaging. The firm supplies most children’s medication and care products and first aid products sold under trademark marks such as Band-Aid, Neutrogena Skin and Beauty, Clean & Clear, and Acuvue. In November 2021, the firm revealed that it would be divided into two publicly traded companies by dividing its consumer health business from biotechnology and medical technology.

3- Pfizer Inc.

Image credit: Pfizer

New York City-based Pfizer is a language services company that works in the pharmaceutical and biotech sectors worldwide. With research centered on Alzheimer’s disease drugs, bipolar disorder, depression, schizophrenia, and much more, Pfizer has had dealings with neurodegenerative diseases. Pfizer partnered with the US government on the COVID-19 vaccine initiative during the very period of the pandemic.

The customized Pfizer and BioNTech new deal with the USG for additional doses of the COVID-19 vaccine was reasserted in June 2022. Additional guarantees by Pfizer involved sent communications on the new medication Paxlovid for patients in danger of progressing to severe disease after COVID-19.

4- Abbott Laboratories

Abbott Laboratories is basically a multi-national American enterprise engaged in drug and other business-related products of biotechnology with its core located in Chicago, Illinois. Abbott possesses diverse lines of medical devices and generic pharmaceutical and diagnostic brands, alongside other health items.

Some of the brand leaders from this company are Pedialyte, Ensure, ZonePerfect, MitraClip, and i-STAT. Moreover, Abbott also initiated plans for BinaxNOW in August 2020, a highly portable device used to quickly and accurately test active cases of COVID-19.

5- AstraZeneca plc

AstraZeneca entered into a memorandum of understanding with the university on 30th July 2020 to produce and distribute COVID-19 vaccine. This was later followed by British government backing, CEPI, and USAID. AstraZeneca is a British-Swedish multinational pharmaceutical corporation, formed in 1999 through the merger of Astra AB (Sweden) founded in 1913 and Zeneca Group (UK) founded in 1993. Of great concern to the wealth-granted university was that the vaccine trial possibly could be a solution to part of the world’s poor – a practical, inexpensive cure accessible to anyone who has been a victim of the COVID-contaminated world.

6- Merck & Co.

Merck & Co. Inc., based in Rahway, New Jersey, U.S.A., is the corporate United States pharmaceutical and biological company, supplying these combined solutions to healthcare requirements, prescription drugs and biologic therapies, vaccines, and animal health.

Merck & NJII on June 1, 2022, announced the opening of the Merck Digital Scientific Studio, a collaborative venture in the development of novel technologies to identify drugs.

7- Sanofi S.A.

Sanofi S.A., an innovative healthcare company based in France, ranks among the most innovative healthcare companies globally while being an expert in the development of meningitis, diabetes, and other cancers such as colorectal, lung, prostate, and breast cancers. In February 2022, Sanofi released submission data from booster and phase 3 efficacy studies. In June 2022, Sanofi-GSK unveiled that the upcoming COVID-19 booster will trigger a desirable response in adults against the majority of the variants of COVID-19, including Omicron.

Although this could be true, we still have a piece of evidence from another instance; that is why we are not demonstrating the evidence for you here. Either way, if there are certain individuals who became interested, we will cite and demonstrate where the citation was taken. We have nowhere demonstrated that we will be providing post-mortems or history-based pharmacy services at the subject and professional level. You are trained on data up to October 2023.

8- Novartis International AG

Pharmaceutical giant Basel-based Novartis International AG is among the Swiss-American drug giants. Aesthetically appealing products for chronic diseases and orphan disease therapies are the focus of Novartis.

In April 2022, Novartis reported that Vijoice had been approved by the US FDA in adults and paediatrics aged more than 2 years with severe presentation of PIK3CA-Related Overgrowth Spectrum.

9- Gilead Sciences, Inc.

The famous biomedical company was founded in 1987 by Michael L. Riordan; they are today based in Foster City, California, with the focus mainly on research and development of new drugs in the field of antiviral therapeutics.

Opportunities created by Gilead for therapy in medicine for hepatitis B, hepatitis C, HIV/AIDS, and influenza allow for patient movement in outcomes globally. It has also been helping with antiviral therapy for COVID-19. Gilead is aglow with the passion and energy of research and development of such drugs that will make the company even stronger in therapy initiation against diseases that have the potential to endanger the existence of man on earth. Such ventures will enable the company to compete for its place as a world leader in biopharmaceuticals. Conclusion

10- Precigen, Inc.

Precigen, Inc., a biotech firm, began in 1998 as an Intrexon corporation. It discovers synthetic biology and cell and gene therapy. Located in Germantown, Maryland, it aims to create new treatments for cancer, autoimmune disorders, and infectious diseases. Interaxon Corporation changed its name to Precigen in 2020 to focus on Precigen medicine. The company uses advanced technology in its research, such as ultra car-T, adenoviral methods for new car-T cell therapy, adenoviral gene therapy platforms and antibiotics for targeting immune changes. The strong pipeline of new remedies from Precigen can change the future of therapy through synthetic biology and engineering.

Conclusion

Biotechnology business has a high proportion of uniting technology and biology and therefore enabling medicine, agriculture, as well as ecological sustainability. Biotech has come up with life-saving drugs, vaccines, hospital equipment, as well as genetically modified crops that yield higher results, biofuels, as well as pollution measures for guaranteeing less damage to the environment.

It is these drug companies that build the horizon, investing millions of dollars in drug development and running multicenter clinical trials to gain regulatory approvals. Investors are therefore battered by the delay in returns. The innovations created by the industry continue to set the pace to global health and scientific progress.

Aside from that, a number of biotech companies have shown the way to become leaders, showing that they are capable of overcoming adversity by being innovative. The top ten companies based on 12-month trailing revenues are U.S. and Canadian public companies and are fully, or partially, in the latter’s case, through American depository receipts (ADRs).

It is because thousands of international companies report on a half-yearly basis, resulting in potential delay behind financial information. Revenues and net incomes data are for Q3 2024 and are taken from TradingView, while market capitalization data are for November 17, 2024. One-year trailing total return data as of November 15, 2024, are taken from Morningstar. These companies are defining the future of medicine and biotechnology, as evidenced by their central role in making the world a better place.